AICAR
AICAR here means the AICA nucleotide. It is a chemical, not a peptide. The US GSRS gives AICAR and acadesine separate records. The two records do not point to the same thing. The EU status remains unclear. The basis for tier B also remains unclear.
What substance does AICAR identify?
US FDA/NCATS GSRS uses the name AICAR. It also uses AICA ribonucleotide. GSRS lists it as a chemical. These fields were checked on 24 August 2026.
Is acadesine the same substance?
No. The official records have different names and identifiers.
| GSRS record | Other GSRS name | UNII | CAS |
|---|---|---|---|
| AICAR | AICA ribonucleotide; aminoimidazole carboxamide ribonucleotide | F0X88YW0YK | 3031-94-5 |
| Acadesine | 5-aminoimidazole-4-carboxamide riboside | 53IEF47846 | 2627-69-2 |
The table was checked against GSRS on 24 August 2026. Acadesine is not an alias in this entry. A name alone can point to the wrong row. That is why this page leads with IDs, not a sales name. The IDs let a reader check which row a source means.
PMID 17513706 studied the riboside form (claim checked 24 August 2026). PubMed files it under acadesine, not this AICAR record. PubMed lists Wellcome Trust support. This entry does not transfer the paper's findings.
What does evidence tier B establish?
The internal register assigns tier B (field checked 15 August 2026). Its exact substance basis is now unclear. This page attributes no human result to AICAR.
What is the recorded EU status?
The EU field remains unclear (field checked 15 August 2026). No primary AICAR source is linked to it. EU status and evidence tier remain separate.
When was AICAR first recorded?
The sources on this page give no first-observed month (checked 24 August 2026). The field stays unclear instead of showing an unsupported date.
What other names identify AICAR?
The first row in the table lists the GSRS names for AICAR. The second row belongs to a different record. The distinction was checked on 24 August 2026.
Which identifiers belong to AICAR?
The first row gives the official AICAR identifiers. GSRS was checked on 24 August 2026.
What does this register entry cover?
This entry keeps identity, evidence tier, EU status, and vial evidence apart. It has no test result for a specific vial. A vial can only be assessed from evidence about that vial.